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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
18.18
Human Site:
S569
Identified Species:
28.57
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
S569
E
A
K
Q
E
V
P
S
W
L
E
N
M
A
Y
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
S567
E
A
K
Q
E
V
P
S
W
L
E
N
M
A
Y
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
P818
V
E
A
K
Q
E
V
P
S
W
L
E
N
M
A
Dog
Lupus familis
XP_861268
662
73195
S569
E
A
K
Q
E
V
P
S
W
L
E
N
M
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
S569
E
A
K
Q
E
V
P
S
W
L
E
N
M
A
F
Rat
Rattus norvegicus
NP_001102328
659
72976
P566
V
E
A
K
Q
E
V
P
S
W
L
E
N
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
S555
E
A
K
Q
E
V
P
S
W
L
E
N
M
A
Y
Chicken
Gallus gallus
NP_001025971
651
72031
E558
L
L
V
E
A
K
Q
E
V
P
S
W
L
E
N
Frog
Xenopus laevis
P24346
697
77284
A604
L
L
D
L
L
V
E
A
K
Q
E
V
P
S
W
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
A595
L
L
D
I
L
V
E
A
K
Q
E
V
P
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
F688
T
K
Q
E
I
P
S
F
M
E
D
M
S
S
D
Honey Bee
Apis mellifera
XP_391829
701
78642
E609
L
L
V
E
A
N
Q
E
L
P
P
W
L
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
D533
E
A
N
Q
E
V
P
D
W
L
T
R
Y
A
S
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
G525
N
N
Q
N
I
V
K
G
L
M
E
I
L
N
E
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
A581
E
A
N
Q
E
V
P
A
F
L
E
T
I
A
R
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
0
N.A.
100
0
13.3
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
13.3
N.A.
100
13.3
33.3
33.3
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
60
13.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
14
0
14
0
0
20
0
0
0
0
0
47
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
0
0
0
0
7
0
0
7
0
0
7
14
% D
% Glu:
47
14
0
20
47
14
14
14
0
7
60
14
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
14
0
0
0
0
0
0
7
7
0
0
% I
% Lys:
0
7
34
14
0
7
7
0
14
0
0
0
0
0
0
% K
% Leu:
27
27
0
7
14
0
0
0
14
47
14
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
7
0
7
34
14
0
% M
% Asn:
7
7
14
7
0
7
0
0
0
0
0
34
14
7
7
% N
% Pro:
0
0
0
0
0
7
47
14
0
14
7
0
14
0
0
% P
% Gln:
0
0
14
47
14
0
14
0
0
14
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% R
% Ser:
0
0
0
0
0
0
7
34
14
0
7
0
7
20
7
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% T
% Val:
14
0
14
0
0
67
14
0
7
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
40
14
0
14
0
0
14
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
27
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _